Bournemouth vs Manchester City
Eddie Howe has endured a miserable start to the season with two defeats and no goals. That is unlikely to change against Manchester City, who have spent over £200million this summer.
City will at least travel to the South Coast without new signing Kyle Walker, who was sent off on his home debut against Everton. Pep Guardiola's men are at 3/1 to win by exactly one or two goals, but the bookies seem to think it's more likely they'll cruise to a victory by three or more goals. Bournemouth are yet to win a league game against City, and they've lost by four goals in three of their last four meetings.
Manchester United vs Leicester
The Red Devils have been on fire so far with eight goals in two games, thanks in no small part to Romelu Lukaku. The Belgian is at 2/1 to score another brace. However, Leicester should put up more of a fight than West Ham and Swansea as they've enjoyed an impressive start to the new campaign.
Crystal Palace vs Swansea
Two of last year's survivors go head to head and based on their efforts so far, it will be no surprise if they're in for another relegation scrap this time around. Palace are slight favourites at 10/11, but purely on account of being at home. The Eagles are yet to keep a clean sheet in all competitions, so we're backing a home win and both teams to score at 3/1.
Watford vs Brighton
Marco Silva has enjoyed a fantastic start to life as Watford manager. It's going to be a tough season for Brighton, meanwhile, as they are yet to pick up a point or score a goal. A Watford win and clean sheet is at 2/1. Andre Gray will be looking for his first goal for the Hornets, and the former Burnley forward is at 4/1 to open the scoring.
Huddersfield vs Southampton
Southampton are at evens to pick up a win at newly-promoted Huddersfield, who will have surprised a few people by winning their opening two games. A draw is at 12/5, which could be promising given that the Saints haven't been convincing. Their hopes this term should be boosted by the return of Charlie Austin, who missed so much of last season through injury. The striker is at 7/4 to score in 90 minutes.
Newcastle vs West Ham
The problems are piling up for both Rafa Benitez and Slaven Bilic already. It's probably too early to describe this game as make or break for either manager, but with their respective sides hovering in the bottom four, they can't another defeat. Bilic will be pinning his hopes on Javier Hernandez, who scored a brace last weekend. The Mexican is at 15/8 to score in 90 minutes, with West Ham the slight outsiders at 21/10. Either side comes with a huge risk, however, as they are both fast approaching crisis mode.